OpenSlide is a C library for reading whole slide image files. From 3.4.1 until 4.0.1, OpenSlide's parse_level0_xml() processing in src/openslide-vendor-ventana.c accepts nonpositive row or column tile counts from a crafted Ventana BIF file. The invalid counts produce attacker-controlled relative memory offsets and allow arbitrary values to be written at those offsets, affecting all supported platforms and configurations and resulting in a crash or potential arbitrary code execution. This issue is fixed in version 4.0.1.
CVE-2026-48977
This high-severity CVE scores 7.7 under a secondary CVSS source (NVD's own analysis pending). EPSS exploit probability: 0.3%, top 78% of all CVEs by exploit prediction. GitHub Security Advisory data not yet ingested — confidence will rise once GHSA publishes (typical lag: hours to days for open-source ecosystem CVEs; never for infrastructure-only CVEs).
- High severity, but no confirmed exploitation yet
No vendor fix yet — apply a workaround or compensating control (WAF / firewall / segmentation) and watch for a patch.
- CVSS v3
- 7.7
- EG Score
- 7.7(medium)
- EG Risk
- 35(Track)EG Risk 35/100SSVC: Track
EG Risk is EchelonGraph's 0–100 priority score: it fuses intrinsic severity with real-world exploitation and automatability so you can rank equal-severity CVEs and fix the most dangerous first. Higher = act sooner. Distinct from the 0–10 EG Score (severity).
How it’s computedSeverity77% × 45%Exploitation0% × 40%Automatability0% × 15%Action: Routine — remediate on your standard cadence. - EPSS PROB
- 0%
- EPSS %ILE
- 22%
- KEV
- Not listed
Published
September 17, 2026
Last Modified
September 18, 2026
Advisory Details (4)
Auto-updated Sep 17, 2026OpenSlide 4.0.1
Patch available: openslide/openslide v4.0.1
https://github.com/openslide/openslide/releases/tag/v4.0.1commit 2be88bd782d9 (openslide/openslide)
Patch available: openslide/openslide v4.0.1 (contains commit 2be88bd782d9)
https://github.com/openslide/openslide/commit/2be88bd782d9fff46de8e56a99baca523e7917b3ventana: fail if area has invalid tile count
Patch available: openslide/openslide v4.0.1 (PR #751 merged 2026-06-06)
https://github.com/openslide/openslide/pull/751Arbitrary memory write with crafted Ventana BIF file in OpenSlide 3.4.1 and 4.0.0 (CVE-2026-48977) · Advisory · openslide/openslide · GitHub
https://github.com/openslide/openslide/security/advisories/GHSA-mxg2-48g7-fmwcWeakness Classification(3)
MITRE Common Weakness Enumeration — the root-cause categories this CVE belongs to.
Data Freshness Timeline
(refreshed 6× in last 7d / 6× in last 30d)
Each row is a source pipeline that fetched or updated this CVE on that date, with what changed. For example, "NVD update" means NVD published or revised its analysis for this CVE; "MITRE cvelistV5" means we ingested or refreshed it from the CNA feed. Most recent first.
- 2026-09-18 20:33 UTCEG score recompute
- 2026-09-18 20:10 UTCEG score recompute
- 2026-09-18 19:28 UTCEPSS rescore
- 2026-09-17 21:20 UTCEG score recompute
- 2026-09-17 20:34 UTCEG score recompute
- 2026-09-17 20:34 UTCMITRE cvelistV5first tracked
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Dependency Blast Radius
Explore the affected products and dependency analysis for CVE-2026-48977
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